New treatments for diabetes may lie in metabolic
Collaborative work carried out by researchers at McGill University, Kyoto University and Inserm/University of Paris reinforces these results. This work has revealed an association between diabetes and the metabolite 4-cresol, an organic compound produced by the intestinal flora and also present in certain foods.
"While there is currently a lack of therapies to stimulate pancreatic beta cell proliferation and improve beta cell function in order to restore insulin secretion, these results are particularly encouraging. Moreover, they confirm the impact of the intestinal flora on human health, demonstrating the beneficial role of a metabolite produced by intestinal bacteria, and opening up new therapeutic avenues in diabetes, obesity and hepatic steatosis," says Dominique Gauguier, a researcher at INSERM/Université de Paris and senior author of the new study.标签：